Zinc (Zn) is an essential trace element for cellular processes such as oxidative stress regulation.
In vivo, Zn supplementation increased CL size but reduced plasma P4 levels.
In vitro, 0.8 μg/ml Zn decreased P4 synthesis and ROS levels while enhancing cell viability, whereas 1.2 μg/ml Zn had no significant effect compared to the control.
Zn modulates luteal function in a dose-dependent manner, reducing oxidative stress while impairing P4 production.